The cause of itchy blisters on the hands and feet may be herpes sweat, tinea pedis, should be timely consultation to identify the cause. 1. herpes sweat: herpes sweat etiology and pathogenesis is not clear, may be related to mental factors, infection, local allergies (nickel, chromium metal, etc.), manifested in the palms of the hands and soles of the feet, the fingers (toes) between the diffuse distribution of deep in the sex of the small blisters, the blister wall is thick, the blisters are transparent, accompanied by itching or burning pain. 2. tinea pedis: tinea pedis is caused by fungal infection, in which blister type manifests itself as small blisters on the hands and feet and very itchy, lesions for the first time for the pinpoint size of the deep in the blisters, blister liquid clear, not easy to break, can be fused into a multi-compartmental blisters. In addition to these factors, do not rule out that there are other causes, it is recommended that patients seek medical attention in a timely manner to clarify the cause of the disease, follow the doctor’s instructions for standardized treatment.