Albumin to globulin ratio refers to the ratio of albumin to globulin. A high globulin can lead to a low white globulin ratio, which can be caused by chronic inflammation, autoimmune diseases, some blood diseases and so on. 1. Chronic inflammation: If the patient is infected with chronic inflammation, such as tuberculosis, subacute infective endocarditis, a high globulin to low albumin ratio will occur. At this time, it is necessary to consult a doctor in time, under the guidance of the doctor, anti-tuberculosis treatment and treatment for subacute infective endocarditis. 2. Autoimmune diseases: If you suffer from autoimmune diseases such as certain types of hyperthyroidism or ulcerative colitis, you may have a low globulin-to-albumin ratio and need to seek medical attention. For hyperthyroidism, oral methimazole tablets, nuclear iodine 131 treatment, surgical treatment, etc.; for ulcerative colitis, oral sulfapyridine colon capsules and other medications. 3. Hematological diseases: There are mainly multiple myeloma, lymphoma and other hematological diseases, which can also lead to high globulin and low albumin ratio. The patient should consult the doctor in time for the treatment of multiple myeloma and lymphoma. If the patient has a low globulin to albumin ratio, he should consult a doctor in time to find out the cause of the disease and carry out standardized treatment under the guidance of the doctor.