The statement that normal blood creatinine means normal kidney function is not true.
Creatinine is the metabolic end product of creatine in muscle tissue. Creatinine does not bind to protein in the blood and can pass freely through the glomerulus, which is currently the most commonly used indicator to indirectly reflect the glomerular filtration function. When the renal parenchyma is damaged and the glomerular filtration rate is reduced to a critical point (when the glomerular filtration rate drops to 1/3 of normal), the blood creatinine concentration will rise significantly.
Blood creatinine can only be used as a criterion to judge whether there is kidney disease, but it does not mean that normal blood creatinine renal function is normal. Moreover, blood creatinine cannot accurately and timely respond to kidney function; while kidney function has a certain compensatory ability, blood creatinine may not be elevated in the early stage of the disease, and at this time, blood creatinine may be within the normal range through the examination.
Such as nephritis, kidney stones, pyelonephritis, etc., the blood creatinine of patients with these diseases can often be normal, so it is necessary to combine with the urine routine, blood β2-microglobulin, cystatin C, urinary tract ultrasound and other related indicators to further assess the level of renal function.
If patients need to improve the renal function test, it is recommended to go to regular hospitals for consultation, and have the test results prescribed and evaluated by professional doctors.