Magnesium isoglycyrrhizate is not suitable for hypertensive patients. Magnesium isoglycyrrhizate is a fourth-generation glycyrrhetinic acid preparation, which is a multifunctional hepatocyte protective agent. Because glycyrrhetinic acid preparation can cause pseudo-aldosteronism, such as hypokalemia, elevated blood pressure, water and sodium retention, swelling and other adverse effects, isoglycyrrhetinic acid magnesium injection is unsuitable for patients with hypertension. Magnesium isoglycyrrhizate injection can significantly reduce the liver damage caused by anti-tuberculosis drugs, no significant adverse reactions were seen, and the drug is relatively safe to use. Hypertension is a common and frequent disease in China, the drugs for hypertension often have mutual reactions with other drugs.