Subperitoneal hypodense shadow of the right liver may be caused by liver cysts, hepatic adenoma, hepatic hemangioma or hepatocellular carcinoma, and it should be treated according to the cause of the disease, such as surgical treatment and drug treatment. 1. Liver cysts: for this kind of disease, if there is no obvious discomfort, it can be temporarily treated conservatively with regular review; if it meets the indication of surgery, it can be treated by surgery, such as hepatic cyst incision and drainage, partial hepatectomy. 2. Hepatic adenoma: the treatment of hepatic adenoma is mainly based on surgery, such as tumor resection, hepatic lobectomy and so on. 3. Hepatic hemangioma: if there is no uncomfortable reaction from the body, no treatment measures can be taken, but regular follow-up and review are needed. If the tumor grows rapidly, then surgery such as laparoscopic partial hepatectomy can be considered. 4. Hepatocellular carcinoma: Usually, it needs to be treated by surgery, and secondly, according to the pathological results, radiotherapy and chemotherapy such as fluorouracil should be used in combination after surgery, which can slow down the development of the disease and alleviate the adverse symptoms. There are many causes of right hepatic subperitoneal hypodense shadow, it is recommended to timely examination and active treatment, do not delay the condition. Drugs should be applied under the guidance of a doctor.