The common causes of impaired islet function are as follows: 1. Acute pancreatitis: Impaired islet function due to acute pancreatitis is often transient, and islet function will return to normal when the acute pancreatitis has completely recovered. If the islet function is impaired due to acute pancreatitis, it only needs to be treated with glucose-lowering drugs or insulin for a period of time. 2. hyperglycemia: impaired islet function due to hyperglycemia is common in type 1 diabetes and type 2 diabetes. impaired islet function due to type 1 diabetes requires insulin treatment for life, and impaired islet function due to type 2 diabetes is absolute or relative hypersecretion, if If the blood glucose is very high or glycated hemoglobin is >9.0% in early stage, insulin treatment is needed, and after the pancreatic islet function is restored to a certain degree, it can be changed to oral hypoglycemic drugs.