Celiac disease with intestinal metaplasia may be precancerous. Celiac disease refers to the breakage of the mucosal layer on the surface of organ tissues, but to a lesser extent, not exceeding the muscular layer. Intestinal metaplasia refers to the replacement of normal gastric mucosa by intestinal-type epithelial cells, which are rich in Paneth cells and cup cells and can secrete large amounts of mucus. Helicobacter pylori infection, stimulation by spicy substances, drinking and smoking can destroy the gastric mucosal barrier, leading to superficial breakage of the mucosa and causing erosion. When the cells are often destroyed, the intestinal epithelial cells can grow upwards to replace the normal mucosal cells, and intestinal epithelial hyperplasia occurs. Intestinal epithelial hyperplasia is a kind of precancerous pathological state, and when the area is large, it may become cancerous. Therefore, it is recommended that patients should have gastroscopy regularly, and when intestinal hyperplasia is detected, according to the doctor’s suggestion, they should actively cooperate with the treatment, so that the cause of the disease can be removed and the health can be restored as soon as possible. Adopt good living habits in daily life, pay attention to diet and quit smoking and drinking.