The time for glomerulonephritis to progress to renal failure is related to the type of pathology, the severity of the disease and the patient’s treatment, and should be analyzed on a problem-specific basis. If the pathological type is mild, such as microscopic lesions or no significant concomitant diseases or complications, through active and effective treatment, the disease is in remission and kidney function may remain normal and will not progress to renal failure. If the patient has a more severe pathological type with hyperlipidemia as well as glomerular hyperfiltration state, intra-glomerular hypertension with recurrent infections, venous thrombosis and other complications, such as focal segmental glomerulosclerosis and IgA nephropathy patients, renal function impairment and progressive renal failure may occur within 10 years and renal replacement therapy is required. Patients with glomerulonephritis need to improve the relevant tests, which can be done by checking kidney function, urinary routine, urine protein quantification, or even kidney puncture biopsy to clarify the specific situation, so that the professional doctor can develop a targeted treatment plan as well as determine the prognosis. In terms of life, pay attention to the prevention of colds, avoid staying up late and overworking, and pay attention to a low-salt, low-fat, high-quality, low-protein diet, and actively take Chinese medicine to protect kidney function.