There is no fastest solution for children with colds and blisters in the throat, which may be caused by herpetic pharyngitis, hand, foot and mouth disease, etc. General treatment and medication need to be used according to the cause of the disease. 1. Herpetic isthmus: mainly because of viral infections caused by a disease that often leads to herpes in the oral mucous membrane area, sometimes accompanied by ulcers, which may be secondary to viral infections after a cold. Pay attention to rest, ventilation of the room, drink more water. If the influenza virus infection, the available oseltamivir phosphate oral; if the viral infection secondary bacterial infection can be selected antibiotic treatment, often use cefixime and other drugs. 2. Hand, foot and mouth disease: In addition to oral blisters, there may be rashes in other parts of the body. Pay attention to isolation to avoid cross-infection. Appropriate rest, light diet, good oral and skin care. Attention should be paid to keep the airway open and oxygen should be administered if necessary. Methylprednisolone, hydrocortisone, dexamethasone, intravenous immunoglobulin, etc. should be used in severe cases under doctor’s supervision. All of the above medications should be used under the guidance of a doctor and avoid self-medication. Children with cold throat bubbles, try to be able to go to the hospital, identify the cause, targeted treatment.