Coughing up sputum with clear jelly-like sputum suggests a possible infection of the respiratory system. Sputum culture and drug sensitivity tests should be performed to identify the causative organism and sensitive antibiotics should be given. Clinical studies have found that jelly-like sputum contains a lot of necrotic and liquefied tissue, as well as pathogenic bacteria. Jelly sputum may be caused by pathogens such as Klebsiella pneumoniae, respiratory syncytial virus and influenza virus. When coughing clear jelly-like sputum, sputum culture and drug sensitivity test can be performed under the supervision of a doctor to identify the causative organisms. Bacterial infections can be treated by choosing sensitive antibiotics (e.g. cefuroxime, levofloxacin, meropenem, etc.). Viral infections are treated with supportive symptomatic therapy, and antiviral therapy with drugs such as oseltamivir can be used if it is clear that it is influenza or immunodeficiency is present. Most of the jelly-like sputum is in the lower respiratory tract, such as the lungs and small airways, and its expulsion can be facilitated by expectoration by tapping on the back, nebulized inhalation of expectorants (e.g., acetylcysteine, etc.), and humidification of the airways. In addition, if jelly-like phlegm is present, dietary adjustments can be made by eating more fresh fruits and vegetables and avoiding foods that are too spicy and stimulating. If you are coughing up clear, jelly-like sputum, it is recommended that you consult a doctor to complete the relevant laboratory tests to determine the cause of the disease, and follow the doctor’s instructions to standardize and rationalize the treatment.