Water-soluble vitamins: vitamin B1, B2, B6, C, niacin, folic acid. Fat-soluble vitamins: vitamin A, vitamin D, vitamin E, vitamin K. Characteristics of vitamin B1 action: Involved in glucose metabolism and neurological and cardiac system functions Deficiency manifestations: neurological reactions (dry pediculosis), cardiovascular system reactions (wet pediculosis), Wernicke’s encephalopathy, polyneuritis psychosis Adverse reactions: allergic reactions or shock may occur with high doses Indications: vitamin B1 deficiency caused by the foot disease, Weckel’s encephalopathy, peripheral neuritis, dyspepsia, etc. Adjunctive treatment precautions: Uric acid concentration should be measured in high dose application, which is falsely increased, and urinary bilirubinogen may be falsely positive Interactions: Degeneration and destruction occur in combination with antacids, and degradation can be prevented in combination with calcium edetate Characteristics of vitamin B2 action: Participates in cellular redox system, transmits hydrogen reactions, promotes fat, Deficiency of sugar and protein metabolism: pharyngitis, keratitis, glossitis, lipitis, seborrheic dermatitis of the face, dermatitis of the trunk and extremities, anemia and neurological symptoms, corneal vascular hyperplasia, cataract formation, scrotal inflammation, vaginitis Adverse effects: yellow urine after large doses, occasional allergic reactions, rare hyperthyroidism Indications: vitamin B2 deficiency caused by keratitis, dry lips and cleft tongue, scrotal inflammation, corneal vascular inflammation, Scrotal inflammation, corneal vascularization, conjunctivitis, seborrheic dermatitis, etc. Precautions: May cause yellow urine Interactions: Application of phenothiazine antipsychotics, tricyclic antidepressants, and propofol may increase the body’s demand for vitamin B2 and reduce the absorption of thyroxine and gastrointestinal stimulants. Vitamin B6 action characteristics: the human body can not be deficient in coenzyme; involved in the normal metabolism of amino acids, carbohydrates and fats lack of performance: (1) skin: eyes, nose and mouth skin seborrhea-like skin damage; accompanied by linguitis and stomatitis (2) nervous system: peripheral neuritis; accompanied by joint swelling and tenderness, especially wrist swelling adverse reactions: long-term use of large amounts can cause serious neurosensory abnormalities indications (1) Vitamin B6 deficiency caused by drug poisoning; seborrheic dermatitis, dry lips; prevention and treatment of pregnancy and vomiting caused by anti-tumor radiotherapy and chemotherapy, etc. Precautions: Intake of large amounts of vitamin B6 in women during pregnancy can cause; vitamin B6-dependent syndrome in newborns. Interaction: Isoniazid increases the renal excretion of vitamin B6; causes anemia or peripheral neuritis; may increase the analgesic effect of NSAIDs.