The face of thalassemia can be abnormal, such as forehead and top bulge and enlarged head. 1. Thalassemia is an inherited hemolytic anemia disorder with a low prevalence within the Chinese population. It is mainly an anemia caused by decreased hemoglobin production due to impaired or decreased rate of synthesis of the bead white peptide chain of hemoglobin. 2. Patients tend to have pale face, white lips, decreased appetite, yellow eyes, abdominal distension, growth retardation, mental depression, expressionless face, and weakness. Special facial features: frontal and parietal bulging, enlarged head, bulging cheeks, collapsed nose, protruding upper jaw and teeth. Some children will have chronic ulcers on the lower limbs. 3. When combined with acute infection, the above symptoms will be significantly aggravated, and there may be fever, poor appetite, diarrhea and other symptoms. If the above symptoms occur, it is recommended to go to the hospital in time for early and regular treatment.