High blood sugar body weakness needs to be clear about the causes of body weakness, and then symptomatic treatment, common causes of body weakness include high blood sugar, low blood sugar, combined with other diseases and so on. 1. High blood glucose: poor blood glucose control, high blood glucose will cause fatigue, can be relieved by taking glipizide, metformin hydrochloride, pioglitazone hydrochloride tablets and other medicines or by injecting insulin. 2. Low blood sugar: For patients with high blood sugar, when applying hypoglycemic drugs, hypoglycemia may occur, which is manifested as weakness, and glucose needs to be given orally or by injection. 3. Combination of other diseases: Hyperglycemia patients may be combined with other diseases, such as viral infections, which will also be manifested as weakness, and need antiviral symptomatic treatment. When the situation of high blood sugar body weakness, should go to the hospital in time, to clarify the cause of the disease, under the guidance of the doctor to use drugs, do not use drugs, so as not to aggravate the condition.