Erythromycin ointment and erythromycin ophthalmic ointment have different indications and adverse reactions: 1. Different indications: erythromycin ointment is used for the treatment of small burns, purulent skin diseases, skin ulcers and other infections. Erythromycin ophthalmic ointment is used for eye infections caused by sensitive bacterial infections, such as blepharitis, conjunctivitis, trachoma and so on. Sensitive bacteria are gram-positive bacteria, Chlamydia trachomatis and so on. 2. Adverse reactions are different: erythromycin ointment adverse reactions occasionally see skin irritation and allergic reactions. Erythromycin ophthalmic ointment can lead to eye pain, persistent redness and irritation, vision changes and other adverse reactions after use. Erythromycin ointment should be used externally only, avoid contact with eyes and other mucous membranes (e.g., mouth, nose, etc.). Erythromycin ophthalmic ointment is for ocular use, avoid contact with other mucous membranes (e.g., mouth, nose, etc.). If there is a need to take medication, please follow the doctor’s instructions to choose the appropriate medication. If redness, swelling, itching, burning sensation and other symptoms occur at the site of application, stop the medication immediately, clean the site of application and consult your physician.