Atrophic gastritis is not necessarily cancerous, and there are cases where a lifetime without cancer exists. In general, the chance of cancer in simple atrophic gastritis is not high, and there are cases where cancer does not occur in a lifetime. The risk of gastric cancer is greatly increased in moderate to severe atrophic gastritis with moderate to severe intestinalization or atypical hyperplasia. Patients with severe atrophic gastritis with moderate or severe intestinal epithelial hyperplasia and severe atypical hyperplasia, or patients with positive carcinoembryonic antigen, have high cancer rate and should be highly valued and need to be followed up on a regular basis, with repeat gastroscopy every 3~6 months. Therefore, not all atrophic gastritis will be transformed into cancer. If diagnosed with atrophic gastritis, treatment should be carried out under the guidance of a doctor to avoid delay.