The antiviral drugs for hepatitis B are as follows: 1, interferon class: there are long-acting drugs and short-acting drugs, long-acting drugs are Pyroxin; 2, nucleoside analogues: there are currently six types of these drugs, lamivudine for clinical use, adefovir, tipifudine, entecavir, tenofovir, tenofovir’s second-generation product propofol tenofovir, also known as TAF. The rate of drug resistance is high, and now it is hardly used. Adefovir is less resistant, but the onset of action is slow and there are many adverse reactions, and now it is slowly withdrawing from the category of antiviral drugs. Tebivudine also has a high resistance rate, and is now hardly used. So now the widely used and more used are entecavir and tenofovir.