During the period of taking kynurenine tablets breakthrough bleeding should stop using the drug in time, go to the hospital for a detailed examination, identify the cause of the disease under the guidance of the doctor to actively intervene in the treatment. Norethindrone tablets are more commonly used gynecological drugs in the clinic, which can be used to treat menstrual disorders, uterine bleeding and other diseases. However, when breakthrough bleeding occurs during the taking of the drug, it may be related to the improper use of drug dosage. In this case, it is recommended that the patient immediately stop using the drug and go to the hospital for a detailed examination to clarify the cause of the disease and then actively intervene in the treatment. At the same time, patients should strictly follow the doctor’s instructions to take norethindrone tablets, do not self-medication, so as not to cause other serious problems. If breakthrough bleeding occurs during the administration of kynurenine tablets, it is recommended that the patient consult a doctor in a timely manner to determine the cause of the disease and to carry out targeted treatment under the guidance of the doctor.