sma is spinal muscular atrophy, mainly characterized by progressive muscle weakness and myasthenia gravis, which can be classified into type 0~4 according to the age of onset and severity. Type 1.0: It is the onset of the disease before birth. During the fetal period, it shows intrauterine growth restriction, excess amniotic fluid, pulmonary dysplasia, skeletal abnormalities, etc.; at birth, it has severe muscle weakness with bilateral facial paralysis, multiple joint contractures, congenital heart defects, etc. 2.1 Type 1: Also known as infantile type, the disease usually starts within 6 months after birth, manifested by a rapid onset of symmetrical muscle weakness, loss of tendon reflexes, muffled cries, progressive respiratory failure, heavy thoracic deformity, and “frog legs” when lying down. 3.2 Type 2: Also known as the intermediate type, which usually develops at 3 to 15 months of age. The manifestations include inability to sit and stand unaided, muscle weakness and lower limb obstruction, tongue muscle atrophy with muscle fasciculation, dysphagia, respiratory insufficiency, and progressive scoliosis. 4.3 Type 3: Also known as adolescent type, it mostly develops between 18 months and adulthood. The patient can walk independently, but the muscle weakness is progressive, with the lower limbs being heavier than the upper limbs, which may lead to severe impairment of daily life and gradual reliance on a wheelchair. 5.4 Type 4: Also known as late-onset type, it has the mildest clinical symptoms and most often develops after the age of 30. People with this type have mild symptoms of muscle weakness and atrophy, and can maintain their ability to walk throughout their life without any impact on their life expectancy. People with these symptoms are advised to seek prompt medical attention and active treatment.