Catcalling syndrome is a chromosomal disorder, which has a low incidence in the population. The reason is that the baby cries like a cat within one year after birth, so it is called catcall syndrome, which will gradually disappear as it grows older. It is accompanied by special facial features, such as small head, full-moon face, wide eye spacing, low nasal bridge, small jaw, misaligned bite of teeth, small hands and feet, through hands, etc. It is also accompanied by deformities of bones, heart and kidneys. Babies with hypotonia during the birth period and gradually increase in muscle tone with age, most have delayed growth and development, accompanied by severe mental retardation. Most can live into childhood and a few can live into adulthood. There is no special treatment and rehabilitation is required.