Rifampicin capsules may lead to abnormal liver function, at which time there may be yellowing of the skin. Of course, the yellowing of the skin also needs to rule out other factors, such as cholecystitis, cirrhosis and so on. Rifampicin is a commonly used anti-tuberculosis drug, there are certain adverse reactions, among them, hepatotoxicity is also one of the more common adverse reactions, there may be abnormal liver function, if bilirubin is elevated there may be yellowing of the skin, and in some cases, there will be yellowing of the urine, yellowing of the eyes. Therefore, during the administration of rifampicin, attention should be paid to monitoring liver function, if there are liver function abnormalities, it is necessary to adjust the medication, under the guidance of the doctor to choose the drug with less liver injury, and if necessary, appropriate liver-protecting treatment. Normally, you should use tuberculosis drugs regularly, and try to drink more water during the use of rifampicin to promote the metabolism of the drug and reduce the probability of adverse reactions, and the specific use of the drug needs to be carried out under the guidance of a doctor. Also do not eat spicy stimulating greasy food, try not to stay up late and labor. Of course, if the skin is yellow, it is not necessarily caused by rifampicin, but also need to rule out the existence of liver and gallbladder diseases, such as cirrhosis, cholecystitis, gallbladder stones or tumors caused by the doctor’s guidance should be examined clearly.