The danger of hypertension is aptly described as a “silent killer,” said Venezuelan cardiovascular specialist Igor More in a media interview on World Hypertension Day in 2006: “Hypertension is It is the ‘silent killer’ that kills or disables people, but it is treated ‘too gently’. If someone is diagnosed with cancer, he or she will immediately feel terrified; if he or she is diagnosed with hypertension, he or she will not feel bad. In fact, four times as many people die from hypertension as from cancer. Hypertension initially causes little discomfort, but when it does, the symptoms can be death from stroke or myocardial infarction.” Specifically, the organ systems that can be affected by hypertension include the arteries and heart, as well as the kidneys, the central nervous system (brain) and the retina. In the case of the kidneys, for example, the narrowing or even occlusion of the lumen caused by the involvement of the small renal arteries leads to a series of pathological changes in the kidneys, which eventually leads to renal failure and uremia – and it is only then that the theory of nephropathy, proposed by Richard Burritt in 1827, has been definitively linked to hypertension. Similarly, the involvement of the retina is due to the spasm and sclerosis of the small retinal arteries, resulting in hemorrhage and other lesions in the retina, which can lead to blurred vision and even blindness. Even some people who have some understanding of the dangers of hypertension seem to be unaware of the dangers of hypertension to the kidneys and retina, because most people die from heart and brain complications before they develop serious kidney and retinal lesions. Due to the presence of high blood pressure, small arteries in the brain can undergo a series of changes from spasm to sclerosis, and the blood vessels in the brain are weak and even more fragile after sclerosis, plus under the effect of long-term high blood pressure, small arteries in the brain are prone to the formation of tiny aneurysms, which are prone to rupture and bleeding when the pressure fluctuates in vascular spasm. In addition, on the basis of small arteries in the brain sclerosis and easy to lead to thrombosis caused by cerebral infarction, and softening of brain tissue after infarction can cause bleeding of brain tissue around the lesion …… These cases are collectively known as cerebrovascular accidents, commonly known as stroke or stroke – the less severe is disabling, the more severe is fatal. Of course, because the heart is the core organ of the entire circulatory system, it is the heart that bears the brunt of hypertension. As the saying goes, the heart is the first to get “sick” near the water. Long-term narrowing of the lumen of the small arteries throughout the body leads to a rise in peripheral vascular resistance, the heart is forced to increase its work when ejecting blood, and when the force cannot be reached, the heart muscle will thicken in response, and this remedy will affect the diastolic function of the heart, and over time, the heart function gradually failed. But the worst is not this case, after all, this progressive change can still give both doctors and patients enough time to treat, those patients who also combined with coronary atherosclerosis (hypertension can promote its development) may at any time due to a serious heart attack and say goodbye to this beautiful world.