As long as the remaining kidney is normal, donating a kidney does not have much effect on the body. Although normal people grow two kidneys, one on the left and one on the right, and both kidneys are working during detoxification, research has found that one kidney can do the work of two kidneys, and a prime example is a patient with uremic kidney transplant. Uremic patients have completely lost the function of both kidneys, and one of the treatments is kidney transplantation. Instead of transplanting two kidneys, this kind of patient transplants one kidney, and the transplanted one kidney is able to replace its own two kidneys for detoxification and drainage, and it is more adequate for toxin and water discharge, which can fully meet the physiological needs of the body. From here, we can see that donating a kidney has no great effect on the body, but in the future life need to pay attention to: 1, to avoid nephrotoxic drugs, such as ibuprofen, gentamicin, so as to avoid this one kidney is also damaged. 2, to frequently re-check the urinary routine, kidney function, if found early lesions of the kidney, to timely intervention, to prevent this kidney function is also lost, into the uremic phase.