Thyroid pain may be caused by acute suppurative thyroiditis, subacute thyroiditis, etc. It can be treated with drugs such as cefixime and prednisone according to different causes. 1. Acute suppurative thyroiditis: After the infection of thyroid peripheral tissues, bacteria invade the thyroid gland, resulting in acute suppurative infection of the thyroid gland. The thyroid gland may appear red, swollen, hot and painful, and there may be fever, malaise, anorexia and other symptoms. Cefixime and other antibiotics can be chosen for treatment. 2. Subacute thyroiditis: It may show symptoms such as thyroid pain, swelling, difficulty in swallowing and elevated body temperature. If the pain is more serious, you can take oral prednisone and other hormonal drugs to relieve the symptoms. If the symptoms of thyroid pain persist without relief, you need to seek medical treatment in time, and the medication must be carried out in accordance with the doctor’s instructions.