SLE nephritis is a chronic kidney disease, edema elimination requires immunosuppressive therapy, diuretics for symptomatic management, and diet should also be low-salt, low-fat, high-quality low-protein diet. Immunosuppressive therapy: including hormones and immunosuppressants. Hormones include prednisone, methylprednisolone and so on. Immunosuppressants include cyclophosphamide, mertiomacrophenol ester, azathioprine, cyclosporine, etc. Specific medications should be used under the guidance of a professional physician. Diuretics: including furosemide, spironolactone and so on. When using diuretics, attention should be paid to monitoring water electrolyte disorders. Low-salt, low-fat, high-quality and low-protein: eat less food such as salted vegetables and kimchi, eat less fatty meat and other high-fat food, and control protein intake, focusing on high-quality proteins such as eggs, milk and lean meat. Systemic lupus erythematosus nephritis edema should go to the hospital in a timely manner, under the guidance of a professional physician standardized treatment. The medication should be used in accordance with the doctor’s instructions, do not self-medicate.