Non-steroidal anti-inflammatory drugs, as the first-line drugs for rheumatic diseases, are themselves a large class of drugs that do not contain corticosteroids and have anti-inflammatory, antipyretic and analgesic effects, not hormones. Pain is the damage caused by various exogenous stimuli accumulating in body tissues. It has been proved that many exogenous chemicals can cause pain, and some of them also exist in the tissue cells of the body, and they are released from the damaged cells when foreign business or inflammation occurs, which are also called endogenous pain-causing substances. The common pain-causing substances are stain ions (potassium ions, hydrogen ions), amines, peptides: bradykinin, prostaglandins, etc. Non-steroidal anti-inflammatory drugs are to inhibit the above-mentioned inflammation-causing substances and play a role, so they are not taken only when it hurts, not when it does not hurt, but need to be taken orally for a period of time, gradually reduce the amount, and after 3-4 weeks of oral intake, the effect is not obvious, you can change. Regular blood and urine tests and liver and kidney functions should be carried out during the medication period. The duration of medication depends on the stability of the disease, and can be suspended when the disease is stable.