Usually, berberine hydrochloride tablets can be taken together with cephalosporin antibacterial drugs. It is mainly because berberine hydrochloride tablets belong to anti-infective drugs, such as treating gastrointestinal infections and so on. Cephalosporins belong to antibiotics, mainly for some sensitive bacteria infections. The two have no obvious contraindications, and in some aspects, such as gastroenteritis, can play a synergistic role. However, it should be noted that berberine hydrochloride tablets have some common adverse reactions, such as nausea, vomiting. Cephalosporins also have some common adverse reactions, such as itching and redness of the skin. It is also contraindicated for those who are allergic to berberine hydrochloride tablets or cephalosporin antibacterial drugs. The use of drugs should be carried out under the guidance of a professional doctor, do not use on their own, or arbitrarily increase or decrease the dose.