Polypoid lesion of gallbladder is a general term for all non-lithotropic lesions in which the wall of gallbladder grows into the lumen in the form of polyps. In China, with the widespread use of ultrasound technology, the detection rate of polypoid lesion of gallbladder is getting higher and higher, and its clinical and pathological characteristics and the timing of surgery are widely studied. 1, clinical features: most of the symptoms of gallbladder polyps are similar to those of chronic cholecystitis, mainly manifested as mild discomfort in the right upper abdomen and biliary colic when accompanied by stones, but there are also a considerable number of patients who are asymptomatic and are only found when doing health checkups. It is generally believed that gallbladder polyp is a predisposing factor for gallbladder cancer. In recent years, there are many reports about gallbladder polyp cancer at home and abroad, especially when accompanied with stones, the chance of cancer is significantly increased. Gallbladder polyps, also known as gallbladder augmentation lesions or gallbladder tumors, can be divided into true tumors and pseudotumors when analyzed in the sense of gallbladder tumors. The so-called true tumor refers to the gallbladder polyp caused by the hyperplasia of the gland and muscle layer of the gallbladder itself, which is a kind of tumor in the real sense of the gallbladder. The so-called pseudotumor refers to cholesterol accumulation and crystallization caused by dysfunction and disorder of liver and gallbladder cleaning, inflammatory hyperplasia caused by chronic inflammation of gallbladder, and other proliferative lesions caused by abnormal changes of gallbladder and bile. 2. Pathological features: from the pathological point of view, they include adenomatous polyps (tubular adenoma, papillary adenoma, mixed polyps), cholesterol polyps, hyperplastic and inflammatory polyps, and gallbladder adenomyosis. According to the results of our examination, the pathological features are: (i) cholesterol polyps: the tip is composed of vascular connective tissue with a small amount of mucosal epithelium on the surface and contains a large number of foam-like cells. ② inflammatory proliferative polyp: it is a kind of local tissue hyperplasia with epithelial cells covering the surface and hyperplastic glands in the middle, surrounded by lymphocytic infiltration. ③Gallbladder adenomyosis: refers to fibrous thickening of the gallbladder wall, often infiltrated by lymphocytes and plasma cells, with hyperplastic hypertrophy of smooth muscle cells and thickening of the wall of the confined body. ④ Adenomatous polyps: a large amount of glandular tissue. Papillary adenoma is characterized by a dendritic connective tissue core, covered with highly columnar epithelial cells, and may have a certain amount of endocrine cells (Seritonin cells), with a certain degree of atypical hyperplasia and carcinoma in situ. 3. Surgical indications: the selection of surgical indications for gallbladder polyp-like lesions, namely (1) solitary, non-tipped polyps; (2) polyps larger than 1 cm in diameter; (3) wider base; (4) symptomatic polyps over 50 years of age; (5) thickened gallbladder wall; (6) polyp-like lesions located in the neck of the gallbladder, (7) combined gallbladder stones. (8) Single lesion, less than 10 mm, asymptomatic, age less than 50 years, allowed for observation and follow-up; lesion enlargement or morphological changes should be treated surgically. (9) Doppler ultrasound examination of the lesion with abundant blood supply suggests malignant neoplasm. (10) Polypoid lesions of the gallbladder with significant symptoms and recurrent recurrence.