Lymph node metastasis of colon cancer can be treated by surgery, chemotherapy, targeted therapy and other different treatments.
1. Surgery: some colon cancers can be surgically resected even though they have lymph node metastasis, and patients who are eligible for surgery are preferred to be treated by surgery, and the surgical method of resection of colon segments combined with regional lymph node dissection is often chosen.
2. Chemotherapy: chemotherapy can be used for preoperative chemotherapy for patients with lymph node metastasis of colon cancer to help lower the stage and improve the probability of surgery, and can also be used for postoperative adjuvant chemotherapy for patients with lymph node metastasis of colon cancer to reduce the local recurrence, and can also be used for palliation of inoperable or metastatic patients, and commonly used chemotherapy regimens are capecitabine combined with oxaliplatin, fluorouracil combined with calcium folinic acid and oxaliplatin.
3. Targeted therapy: some patients with liver metastasis, lung metastasis and other advanced colon cancer lymph node metastasis can apply targeted drugs such as cetuximab and bevacizumab if they have wild-type of KRAS, NRAS and BRAF genes.
Patients with colon cancer lymph node metastasis often need the combination treatment of different methods mentioned above. It is recommended that patients choose the suitable treatment method under the guidance of doctors.