Angioimmunoblastogenic T-cell lymphoma is a type of non-Hodgkin’s lymphoma that arises from T lymphocytes and is a highly aggressive form of lymphoma. Because this lymphoma is often distributed along the perivascular area, it is, therefore, called angioimmunoblastoma T-cell lymphoma. This type of lymphoma is characterized by its prevalence in older patients, who often present with systemic symptoms such as high fever, wasting, night sweats, and a host of other symptoms of hypermetabolism. There are also symptoms of localized lymph node enlargement and invasion of other organs. Patients with high fever present with persistent hyperthermia, and even after the application of antipyretic drugs, the body temperature only drops briefly, but the effect lasts longer after the application of hormonal antipyretic agents. Currently, there is no specific treatment for angioimmunoblastoma T-cell lymphoma, but only chemotherapy containing anthracyclines can be used, and the dose of chemotherapy is high, but the treatment effect is not very satisfactory.