Coffee enemas are said to be an anti-cancer regimen but have not been proven effective by the medical community. Coffee enemas should pay attention to the following points: First, the ideal number of coffee enemas is once in the morning and once in the evening, and the most suitable time is one hour after meals. For those who are just starting out, it is fine to do it once a day, and the time can be controlled at 15-30 minutes. Secondly, the acid in coffee can irritate the anal skin and may worsen hemorrhoids or cause anal fissures, prolapse, and anal inflammation, so it is recommended to give warm water to cleanse after the enema is finished. Thirdly, coffee enema is to help remove the waste from the colon and shorten the retention time of the waste in the intestine, and cannot replace the normal daily bowel movement. Therefore, patients can go to the local regular hospital for consultation. According to the doctor’s advice, soap and water or saline enemas can be given, and it is not necessary to choose coffee enemas.