A study conducted by Thomas et al. at the Sree Chitra Tirunal Institute of Medical Science and Technology in India evaluated epileptic seizure patterns in women with epilepsy during pregnancy and predictors of seizures, and published the results in a recent issue of Epilepsia. The study included 1297 pregnant patients with epilepsy and recorded the use of antiepileptic drugs and seizure frequency in the first month of pregnancy and during pregnancy. The study found that 47.8% of patients were seizure-free during pregnancy; had the highest rate of seizure recurrence during the 3 days of the perinatal period; had a higher rate of recurrence in patients with focal epilepsy compared to those with generalized epilepsy (OR: 1.6); had an increased risk of seizures with polypharmacy compared to monotherapy (OR: 2.98); and had a higher risk of seizures during pregnancy in patients with seizures in the first month of pregnancy compared to those without seizures (OR. 15). Multiple regression analysis showed that pre-pregnancy seizures were the most important predictor of seizures during pregnancy.