Six-year-old children with long spots on the face, consider the appearance of freckles, florid chaff rash or hypopigmented vitiligo and other patches of different colors. 1. freckles: may be related to heredity, belong to the common facial brown dotted pigmentation spots, to the cheeks and nose appear lesions mainly, can see light brown pinpoint or rice grain size spots, scattered distribution, can be affected by ultraviolet radiation. 2. florid chaff rash: caused by Malassezia infection, easy to occur in children’s frontal face, there will be a pore-centered border clear punctate papules, lesions can be brown, light brown, reddish, yellowish or white, its color and the patient’s skin color. Chronic course, not standardized treatment often lasts for years. 3. Vitiligo: children’s face or other parts of the body can also occur vitiligo, can be related to genetic factors, neurological factors, autoimmune and other etiological factors, at this time can be found in the face of white pigmentation spots, lesions of varying sizes, and often no self-conscious symptoms. When the child’s face appeared in the unexplained patches, should be timely to the regular hospital medical consultation, clear diagnosis, according to the characteristics of the disease to choose the appropriate treatment measures.