Whether glomerulonephritis is serious and how to treat it are related to the cause of the disease and the type of pathology. If acute glomerulonephritis is treated with rest and anti-infection, it may be cured; chronic glomerulonephritis can be treated with medicines such as captopril and prednisone, and the condition of those with less severe pathologic types will be relieved, which is usually not serious at this time. If the pathologic type is more serious, it may develop into uremia, which is more serious at this time. 1. Acute glomerulonephritis: supportive and symptomatic treatment. In the acute stage, bed rest should be provided, waiting for hematuria to disappear, edema to subside and blood pressure to return to normal. At the same time, salt restriction, diuretic such as furosemide, etc., lowering blood pressure such as the application of Irbesartan and other symptomatic supportive treatment. Penicillin and other anti-infective treatment can also be applied. This disease is a self-limiting disease, most patients have a good prognosis, and it is usually not serious at this time. 2. Chronic glomerulonephritis: ACEI or ARB drugs such as captopril and irbesartan can be applied to lower blood pressure and reduce urinary protein; glucocorticoids and cytotoxic drugs such as prednisone and cyclophosphamide can also be applied. The less severe types of pathology resolve with treatment and are usually not serious at this point. If the pathologic type is more severe, it may develop into uremia, which is more serious at this time. All of the above medications should be used under the guidance of a doctor, avoid self-medication. Patients with glomerulonephritis are advised to go to a regular hospital in time, complete the examination to clarify the cause of the disease, and then give targeted treatment or treatment under the guidance of the doctor.