Pediatric tumors are highly malignant and have a high metastatic rate, so it is very important to achieve early detection and early treatment. Since the clinical symptoms are very similar to some common diseases, pediatric tumors are easily misdiagnosed. At this time, parents should take the responsibility of “gatekeeper”, be highly alert to the following early signals of pediatric tumors, and take their children to the hospital for medical treatment as soon as they are found to be suspicious. When a child suffers from a tumor, there are corresponding symptoms in the skin, lymph nodes, organs and nerves, etc. Parents should pay more attention to observe the child’s tumor. Parents should pay more attention to observe the abnormal symptoms of children, so as to achieve early detection, early diagnosis and early treatment of pediatric tumors. Children with the following symptoms should pay extra attention: (1) Anemia or bleeding with bad “tonic”, unexplained pallor, often accompanied by lethargy, fatigue, loss of appetite, or unexplained bleeding, including bleeding gums, nosebleed, bleeding spots or petechiae on skin, and laboratory tests can be conducted to exclude leukemia. Tumor anemia is different from nutritional disorder anemia in that the latter can be basically improved after proper supplementation of raw materials needed for hematopoiesis (e.g., iron, vitamins and proteins). The former, without formal chemotherapy, even if you take more nutritional supplements, but also “stone sinking into the sea”, in vain. (2) persistent low fever General cold, pneumonia fever, a few days will be good. However, if the unexplained fever lasts for more than 1 week, especially after antiviral and antibiotic treatment is ineffective, you can no longer take medicines at home to deal with it, and you should consult a doctor as soon as possible. Because this is likely to be the clinical manifestation of malignant tumors. The fever of malignant tumor is repeated irregular low fever, when the patient’s body temperature is usually below 38℃. We would like to remind you that when repeated irregular fever occurs, it is best not to use antipyretic drugs arbitrarily, so as not to cover up the condition. The best thing to do is to consult a doctor in time to find out the cause of the disease. (3) Lymph node enlargement Local or generalized lymph node enlargement caused by various pathogenic microbial infections. If the lymph node enlargement does not go down for a long time and there is no pressure and pain sensation, it should be examined in detail to be alert to the possibility of tumors. (4) Unexplained lumps Once lumps are found in the neck, armpit, groin, abdomen and lower back of children, the cause should be identified. Lymph node enlargement in leukemia usually does not cause pain, but the more this kind of seemingly benign “painless lumps”, the more alert. Parents are advised to touch the whole body of their children after they go to bed, and if they feel lumps or hard masses, they should be alert to the possibility of tumor. (5) Abnormal enlargement of limbs and trunk Some bone cancers or rhabdomyosarcoma are indicated by enlargement of limbs or trunk, which should not be regarded as traumatic injury and handled rashly. (6) Unexplained pain Long-term persistent or intermittent pain, such as headache, abdominal pain, joint pain, etc. Neurological symptoms, such as vomiting, unsteady walking, etc., are often present at the same time. Bone pain is mainly hidden pain and distension, mostly occurring in the sternum and limb bones. Most of the joint pains are wandering, appearing and disappearing, and are easily misdiagnosed as acute rheumatoid arthritis. (7) Abdominal distension and vomiting Intestinal tumors may cause intestinal obstruction, resulting in gastrointestinal symptoms such as abdominal distension and vomiting. In addition, don’t take it lightly when your child yells about bellyache or has a distended and bulging stomach; when you change clothes and take a bath, you may want to observe your child’s stomach more often and press it with your hand to see if there is any abnormality. (8) Eye abnormalities or discomforts The eyes of young children produce abnormal reflected light to the light, the eyes are deep, white objects are visible, or eyeballs are bulging forward, eye pain and other eye discomforts. They should go to the ophthalmology department for examination quickly. As with adult tumors, early detection of disease clues is crucial to curing the disease so as to buy treatment time and ensure efficacy. Therefore, parents should do the following: First look, pay attention to changes in the child’s mobility, such as loss of appetite and depression. Second touch, usually give the child a bath, more touch the child’s body whether there are lumps, especially the abdomen, whether there are changes in the shape of the body, whether there is no abnormal lumps appear. Third, listen, pay attention to the child’s complaints, young children who can not speak because of the lesions will cry especially hard, or especially spiritless; can speak the pediatric will tell parents where uncomfortable. Once the above abnormalities are found, they should neither be grassed up nor taken lightly. Should go to the hospital in time to consult the doctor, and carry out the necessary examination, so as not to delay the condition, resulting in lifelong regret.