The cause of premature ovarian failure is not particularly clear at present, and it is considered that it may be related to genetic factors, usual bad habits, autoimmune system diseases, medical injury and other reasons. 1. Heredity: premature ovarian failure may be related to congenital heredity, for example, patients with chromosomal abnormalities may cause congenital ovarian underdevelopment and premature ovarian failure. 2. Bad life habits: If women smoke, drink and stay up late for a long time, it will affect the normal function of the ovaries over time. 3. Autoimmune diseases: If the patient suffers from systemic lupus erythematosus and other immune system diseases, it will cause its own endocrine disorders, which may also lead to premature ovarian failure. 4. Medical damage: if some tumor patients need to do radiotherapy treatment, the long-term use of drugs, may inhibit ovarian function, the phenomenon of premature ovarian failure. Premature ovarian failure is caused by many reasons, it is recommended to go to the hospital in time to improve the relevant examination, to clarify the cause of the disease under the guidance of a professional doctor, and to treat it actively.