HPV refers to human papillomavirus, there are many genotypes, different genotypes of HPV infection can lead to different clinical lesions, mainly divided into high-risk type and low-risk type. HPV16 belongs to a high-risk type, gynecological examination of HPV16 positive that is, infected with HPV16 virus. HPV16 is a high-risk type. HPV16 positive gynecological examination means HPV16 virus infection, which may be caused by sexually transmitted route, indirect contact route, mother-to-child transmission route infection. 1. Sexual transmission: the main way of transmission, through sexual contact, if one party is infected with HPV16, it may be transmitted to the other party. 2. Indirect contact: Close contact with HPV16 positive patients or the use of common household utensils, such as towels, toilets, bathtubs, etc., may lead to infection. 3. Mother-to-child transmission route: If the mother is an HPV16-positive patient, the baby may be infected if the baby passes through the birth canal of the pregnant woman during labor and close contact occurs. HPV16 positivity is associated with cancer and precancerous lesions, so it is recommended to consult a doctor in time and follow the doctor’s instructions for treatment.