Autoimmune cholestatic hepatitis clinically known as autoimmune hepatitis, can use prednisone, azathioprine, ursodeoxycholic acid, budesonide and other drugs, but should be based on the actual situation of the selection of appropriate drugs. 1. Prednisone: can be used in combination with azathioprine for postmenopausal women, obesity, hypertension, osteoporosis, etc.; can also be used alone in large doses for combined pregnancy, malignant tumors, hematopoiesis and other cases. 2. Azathioprine: can be combined with prednisone. 3. Ursodeoxycholic acid: can be used in combination with prednisone, applicable to the combination of cholestasis, overlap syndrome and other conditions. 4. Budesonide: can be used instead of prednisone, applicable to non-cirrhotic autoimmune hepatitis. 5. Others: such as cyclosporine, tacrolimus, etc., applicable to those who are ineffective against immunosuppressants. The use of drugs should be carried out under the guidance of a professional physician, and different degrees of progress of the disease to choose a different treatment program, and even inactive cases do not need to use drugs, do not blindly use their own drugs.