Patients with sore throat and neck pain are likely to have congestion and swelling of the mucous membrane in the throat involving the lymph nodes in the neck. In terms of treatment, it must be actively anti-inflammatory and anti-swelling, and can be treated with cephalosporin or penicillin anti-inflammatory drugs, which are commonly used clinically as amoxicillin capsules or cefixime dispersible tablets. However, patients need to be asked if they have a history of drug allergy before using the medication to avoid allergic reactions. It is also recommended that patients go to the hospital for routine blood tests and C-reactive protein to clarify the degree of inflammation. If the symptoms do not improve after three days of oral medication, it is better to switch to IV antibiotics, commonly used cefazolin or cefuroxime sodium injection, and a skin test is needed before using the medication. Patients need to regularly recheck the blood routine and C-reactive protein to clarify the recovery of inflammation.