A blister-like pimple in the anus may be due to perianal herpes, sinusitis, chronic anal fistula and other causes. 1. Perianal herpes: Perianal herpes is caused by viral infection, local skin is visible with blisters, mostly accompanied by pain and other symptoms. Patients can use drugs under the guidance of doctors for treatment, such as acyclovir cream, lincomycin ointment, mupirocin ointment, etc.; allergy patients are prohibited. 2. Sinusitis: sinusitis may be caused by inflammation due to infection; patients may have anal foreign body sensation, swelling, moisture around the anus, blisters and other symptoms; such as the emergence of such symptoms, patients can be treated with medications under the guidance of a doctor, such as erythromycin ointment, hemorrhoid ointment, metronidazole suppositories, etc., or surgical treatment. 3. chronic anal fistula: chronic anal fistula may be due to rectal perianal abscess, ulcerative colitis, anal canal trauma infection and other reasons; in the anus can be seen in one or more protruding blister-like pimples, overflow of pus or blood, accompanied by itching, pain and other symptoms. Surgical treatment is usually available under the guidance of a doctor. If the patient has the above symptoms, daily should keep the bowel movement, keep the anus clean; pay attention to the diet light, eat more fiber and vitamin rich vegetables and fruits, eat some coarse grains; prohibit spicy and stimulating food, prohibit drinking alcohol and so on. Perianal discomfort symptoms, should promptly go to the hospital, under the guidance of a professional physician, clear causes as soon as possible to give reasonable treatment, not blindly self-medication.