The preferred treatments for stage II squamous lung cancer with six-year history are surgical resection, chemotherapy and other treatments. Lung squamous cancer has correlation with environmental pollution, occupational exposure, smoking, heredity, ionizing radiation and other factors. In the early stage, there are no obvious clinical symptoms, and as the disease progresses, symptoms such as cough, hemoptysis, chest tightness, fatigue and weight loss will appear, and it is mainly classified into stage I, II, III and IV by TNM staging, and can be treated by surgery, chemoradiotherapy and immunotherapy. Stage II squamous lung cancer belongs to the middle stage, which indicates that the cancer cells have metastasized to the lymph nodes near the hilum, and if the patient’s body can tolerate it and is in good condition, it can be treated by radical surgery, and if the patient can’t tolerate the surgery it can be supplemented with chemotherapy and radiotherapy after the surgery. If the patient is not able to tolerate surgery, chemotherapy and radiotherapy can be used after surgery. If the patient is in good health, surgery is preferred, and he/she should go to the hospital in time and listen to the professional doctor’s advice.