Mr. and Mrs. Huang have been married for a few years and have not been able to conceive. A short time ago, they were examined and found to be infected with Mycoplasma genitalium. Is there a relationship between infertility and mycoplasma infection? Mycoplasma infection is not a trivial matter. If you get pregnant with mycoplasma infection, the probability of fetal abortion increases. Mycoplasma infection can also increase the risk of cervicitis, pelvic inflammatory disease, infertility, premature rupture of membranes, preterm labor, and stillbirth. If infected with mycoplasma, it is best to cure it before pregnancy. For patients with cervicitis and pelvic inflammatory disease with mycoplasma infection, they should also be cured of mycoplasma infection before other treatments are done. What to do for mycoplasma infection in pregnant women Except for fetal preservation patients, patients with mycoplasma infection found in early pregnancy are generally left untreated for the time being because the early pregnancy period is the period of embryonic differentiation and should be treated with as little medication as possible to reduce the impact on the embryo. Some mycoplasma-positive pregnant women may turn negative naturally with the continuation of pregnancy. This may be related to the change in mycoplasma’s living environment, which is alkaline (pH 7.6-8.6), and the increase in estrogen levels during pregnancy, which increases the acidity of the vaginal environment and inhibits the growth of mycoplasma. If the patient is still positive for mycoplasma after three months, treatment is required, and antibacterial drugs that do not affect the embryo can be chosen. The symptoms of mycoplasma infection are insidious, and couples should be treated together. More than 70% of women with mycoplasma infection have no obvious symptoms, while men often have symptoms such as urethral discomfort and thin discharge, which are mild and easily overlooked or misdiagnosed, thus delaying the disease. Mycoplasma infection should be treated together with husband and wife, which is crucial to improve the cure rate, reduce the recurrence rate and reduce the production of drug-resistant strains of mycoplasma. Sexual intercourse is prohibited during treatment. Nine conditions require mycoplasma testing 1, preparing for pregnancy. 2. Couples with a history of adverse pregnancy and delivery (fetal abortion, habitual miscarriage, stillbirth, premature birth). 3.Patients with long-term abnormal vaginal discharge, occasional itching of vulva, occasional vague pain or tingling or cramping in the abdomen. 4.Women with mucus or purulent discharge from the cervical canal opening, cervical hypertrophy, and heavy cervical columnar epithelial ectoplasia. 5. Patients with pelvic inflammatory disease who complain of being asymptomatic or untreated for a long time. 6.Patients with infertility who visited the clinic because of problems with the fallopian tubes. 7.Compulsory investigation before pelvic operation in infertility patients. 8.Patients with a history of urinary urgency, frequency and painful urination. 9.Spouses of those with mycoplasma infection.