Ultrasound echoes of hepatocellular carcinoma show inhomogeneous, lumpy or diffuse hyperplasia, in addition to abnormally abundant blood flow signals. Ultrasound is an important means of clinical diagnosis of hepatocellular carcinoma, which is important for early detection and differential diagnosis of hepatocellular carcinoma. Under ultrasound, hepatocellular carcinoma is mainly characterized by hypoechoic masses, some of which are hyperechoic or mixed echoes, expansive, with uneven growth margins and irregular morphology, and portal vein thrombus can be found in some patients. In addition, the blood flow signal of the tumor can be seen clearly under ultrasound, which is often accompanied by curved or round blood vessels in continuous distribution. In addition, ultrasound can now be used to perform ultrasound angiography and other examinations, similar to enhanced CT for differential diagnosis. Ultrasound alone can be used to screen or evaluate liver cancer, but further tests such as CT, MRI, and puncture biopsy are needed after abnormalities are detected. If the ultrasound suggests that the liver occupies uneven echoes, it is recommended to do further enhanced CT or nuclear magnetic resonance to clarify the diagnosis and then timely treatment. It is recommended to go to a regular hospital to evaluate the condition and follow the doctor’s instructions to avoid delaying the condition.