It is possible to take two pills of omeprazole at a time. In fact, the dose to be taken is related to the disease, some diseases can be taken two pills or even more than two pills, some diseases can only be taken once, one at a time, such as the usual gastroduodenal ulcer, one pill at a time, once a day. In case of refractory gastric ulcer, take two pills at a time, once a day; in case of reflux esophagitis, you can take two or three pills at a time, once a day; in case of Chorea syndrome, the initial dose should be given three pills at a time, once a day. Therefore, the patient’s condition is related to the dose given, and certain diseases require more than two pills to be effective.