Tetracyclic antidepressants include mianserin and meptyline, whose mechanism of action is similar to that of tricyclics. Tetracyclic antidepressants and tricyclic antidepressants, which are rarely used in clinical practice, can treat the problems of depression and can also act on the manifestation of symptoms such as anxiety and panic, but the tetracyclic and tricyclic antidepressants commonly used in clinical practice have many side effects, such as cardiotoxicity, and side effects such as dizziness, headache, dry mouth and bitter mouth, so it is important to take these drugs under the The doctor’s arrangement and guidance in person. The current first-line clinical antidepressants are mainly selective 5-hydroxytryptamine reuptake inhibitors, including fluoxetine, paroxetine, sertraline and fluvoxamine. If possible, it is best to choose newer antidepressants.