Lymph node nodules refer to enlarged lymph nodes. Whether a lymph node nodule is important or not needs to be determined based on the specific condition. There are many reasons for lymph node nodules to appear, whether it is important or not needs to be based on the patient’s condition. 1. Lymphadenitis: Infectious diseases such as upper respiratory tract infections, patients will have symptoms such as enlarged lymph nodes in the corresponding areas, which can be gradually recovered after anti-infective treatment, so it does not matter. 2. Lymphatic tuberculosis: Mycobacterium tuberculosis infection can lead to lymphatic tuberculosis, resulting in swelling of infected lymph nodes, which can be cured by isoniazid, rifampicin, ethambutol and other drugs. 3. Connective tissue diseases: such as systemic lupus erythematosus, nodular disease, etc., can lead to lymph nodes appearing nodules, after the use of glucocorticosteroids, such as prednisolone, and immune-modulating drugs, such as interferon and other treatments, can control the symptoms of the enlarged lymph nodes temporarily return to normal. 4. Malignant tumor: lymphatic metastasis of malignant tumor or lymphoma can lead to enlargement of corresponding lymph nodes. At this time, it indicates that malignant tumors have entered the middle and late stages, and the condition is serious and urgent, requiring active treatment. Lymph node nodes should not be important can not be generalized, it is recommended that patients seek timely medical treatment, identify the cause of the disease, the doctor will determine the cause of the disease is important, and be treated accordingly. Drugs should be applied under the guidance of a doctor.