How to diagnose meningitis in a patient with a fever is based on the patient’s clinical symptoms. Patients with meningitis may have a fever accompanied by a severe headache and, in severe cases, jet-like vomiting. Patients may also have meningeal irritation, which can include a strong collar, Koch’s sign, and Bruch’s sign, requiring a medical examination to make a definitive diagnosis. Patients with meningitis may also have symptoms of systemic toxicity, such as fever, malaise, loss of appetite, poor mental health, and, in some cases, irritation or seizures. The diagnosis of meningitis requires lumbar puncture to determine the causative organism, routine biochemical examination of the cerebrospinal fluid, and, if necessary, CT or MRI of the skull to visualize the changes in meningitis and to see the enhancement of the meninges. Treatment of meningitis is mainly symptomatic, such as anti-inflammatory, antiviral or anti-tuberculosis treatment depending on the cause.