The difference between clobetasol propionate ointment and compound clobetasol propionate ointment is different in composition, different in character, different in indication and different in adverse reaction. 1. Different ingredients: Clobetasol propionate ointment is mainly composed of clobetasol propionate, while compound clobetasol propionate ointment is mainly composed of retinoic acid and clobetasol propionate. 2. Different properties: Clobetasol propionate ointment is a white ointment with emulsion base, while Clobetasol propionate ointment is a yellow ointment with greasy base. 3. Different indications: Clobetasol propionate ointment can be used for the treatment of psoriasis, neurodermatitis, intractable eczema, insect bite dermatitis, systemic lupus erythematosus, lichen planus and other diseases. However, compound clobetasol propionate ointment is mainly used for the treatment of psoriasis. 4. Different adverse reactions: patients with clobetasol propionate ointment may appear skin itching, burning sensation, erythema, or capillary dilation, skin atrophy and thinning, folliculitis and other adverse reactions. And patients may experience skin irritation such as dryness, itching, erythema, and flaking with compound clobetasol propionate ointment. There are many differences between clobetasol propionate ointment and compound clobetasol propionate ointment in terms of composition, indications, etc. It is recommended that clobetasol propionate ointment and compound clobetasol propionate ointment can be used under the guidance of a doctor, and it is not advisable to use the medication without authorization. It is worth noting that patients should avoid using Clobetasol Propionate Ointment and Clobetasol Propionate Ointment for a long time or a large area.