Morning stiffness in more than 90% of cases is seen in rheumatoid arthritis and other immune-inflammatory diseases, and treatment is focused on effectively treating the cause. Usually, morning stiffness can be cured by treatment. 1. Rheumatoid arthritis: this is a systemic autoimmune disease mainly characterized by synovial cell proliferation and vascular opacification, often involving multiple systems. Morning stiffness is a common manifestation of acute exacerbation of rheumatoid arthritis, which can be effectively controlled by combined treatment with prednisone and methotrexate. 2. Other immune-inflammatory diseases: other immune-inflammatory diseases such as rheumatoid arthritis, dry syndrome, etc. can also lead to morning stiffness of the fingers, and the inflammation can be effectively controlled by oral prednisone, celecoxib, hydroxychloroquine and other drugs. These medications should be used under medical supervision. Morning stiffness of the fingers may also have other causes, it is recommended to go to the hospital in time to see the doctor, and early regular treatment.