Increased amylase may be associated with acute pancreatitis, acute cholecystitis, perforated peptic ulcer and other diseases. 1. Acute pancreatitis: it is the more common cause of increased amylase, and increased serum amylase may appear in 2 to 12 hours after the onset of the disease. 2. Acute cholecystitis: some patients with acute cholecystitis may have mild elevation of amylase due to inflammation stimulating the pancreas. 3. Perforated peptic ulcer: Elevated amylase may occur due to the flow of amylase-rich intestinal fluid into the abdominal cavity and its absorption or the involvement of the pancreas. In addition, there are many other causes of amylase elevation, such as intestinal obstruction, renal failure, pancreatic cancer, mumps, and drug effects, etc. It is recommended that patients go to regular hospitals in time to clarify the cause of the disease, and then carry out targeted treatment under the guidance of the doctor to minimize the adverse effects of the disease.