Pemphigus is a severe, chronic autoimmune disease. After treatment with hormones as prescribed by the doctor, the dosage will be gradually reduced and discontinued according to the condition, and it usually takes a period ranging from 3 to 5 years, and even some patients need to take small doses of hormones for life to control their condition before their symptoms may be eliminated. Pemphigus is a serious recurrent autoimmune herpetic disease. Usually, if patients take glucocorticosteroids such as prednisone and prednisolone under the guidance of a doctor, the effect is usually seen in about 2 weeks, and the lesions subside, but it requires a gradual reduction of glucocorticosteroids, and it usually takes about 3 years before the symptoms can be eliminated. However, due to individual differences, some patients who are physically weak or immunocompromised may take longer to recover, usually about 5 years, and some patients may need to take small doses of hormones for life to control their condition. The key to a cure for pemphigus is early diagnosis and treatment. For patients suffering from pemphigus, they need to go to regular hospitals as early as possible and cooperate with doctors for standardized treatment according to their own conditions.